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Support >> Publications (Biomedical)
Below is a brief listi of the most recent publications documenting the use of Ocean Nanotech products in a wide variety of biomedical applications. These publications feature both commercially available products, as well as novel technologies in development. For a more complete list of publications, please click here. For papers in optoelectronic and synthetic fields, please click here.

Iron Oxide

  1. Tracking Mesenchymal Stem Cells with Iron Oxide Nanoparticle Loaded Poly(lactide-co-glycolide) Microparticles Nano Lett (Advanced Online Publication) C.Xu, D. Miranda-Nieves, J.A. Ankrum, M.E. Matthiesen, J.A. Phillips, I. Roes, G.R. Wojtkiewicz, V. Juneja, J.R. Kultima, W. Zhao, P.K. Vemula, C.P. Lin, M. Nahrendorf,  J.M. Karp

  2. Assessment and comparison of magnetic nanoparticles as MRI contrast agents in a rodent model of human hepatocellular carcinoma Contrast Media & Molecular Imaging 2012, 7(4) 363-72, L. Bu, J. Xie, K. Chen, J. Huang, Z.P. Aguilar, A. Wang, K.W. Sun, M. Chua, S. So, Z.Cheng, H.S. Eden, B. Shen, X. Chen

  3. The manipulation of natural killer cells to target tumor sites using magnetic nanoparticles Biomaterials 2012, 33(22), 5584–92, E. Jang, J. Shin, G. Ren, M. Park, K. Cheng, X. Chen, J.C. Wu, J.B. Sunwoo, Z. Cheng

  4. Nanobeads-based rapid magnetic solid phase extraction of trace amounts of leuco-malachite green in Chinese major carps Talanta 2012, 97(15), 336-42, L. Guo, J. Zhang, H.Wei, W.Lai, Z.P. Aguilar, H. Xu, Y. Xiong

  5. Noninvasive monitoring of orthotopic glioblastoma therapy response using RGD-conjugated iron oxide nanoparticles Biomaterials 2012, 33(21), 5414-22, F. Zhang, X. Huang, L. Zhub, N. Guo, G. Niu, M. Swierczewska, S. Lee, H. Xu, A.Y. Wang, K.A. Mohamedali, M.G. Rosenblum, G. Lu, X. Chen

  6. Imaging of Her2-targeted magnetic nanoparticles for breast cancer detection: comparison of SQUID-detected magnetic relaxometry and MRI Contrast Media & Molecular Imaging 2012, 7(3), 308-19, N.L. Adolphi,K.S. Butler, D.M. Lovato, T.E. Tessier,J.E. Trujillo, H.J. Hathaway,D.L. Fegan, T.C. Monson,T.E. Stevens, D.L. Huber, J. Ramu, M.L. Milne, S.A. Altobelli, H.C. Bryant, R.S. Larson, E.R. Flynn

  7. Magnetic relaxometry with an atomic magnetometer and SQUID sensors on targeted cancer cells J Magnetism & Magnetic Mat  2012,324(17), 2613-9, C. Johnson, N.L. Adolphi, K.L. Butler, D.M. Lovato, R. Larson, P.D.D. Schwindt, E.R. Flynn

  8. Liver cancer immunoassay with magnetic nanoparticles and MgO-based magnetic tunnel junction sensors J. Appl. Phys. 2002, 111, 07E505, Z.Q. Lei, L. Li, G. J. Li, C.W. Leung, J. Shi, C.M. Wong, K.C. Lo, W.K. Chan, C.S.K. Mak, S.B. Chan, N.M.M. Chan, C.H. Leung, P.T. Lai, P.W.T. Pong

  9. Evaluation of brain tumor vessels specific contrast agents for glioblastoma imaging Neuro Oncol (2012). 14(1), 53-63. B.Tomanek, U. Iqbal,B. Blasiak, A. Abulrob, H. Albaghdadi, J.R. Matyas, D. Ponjevic, G.R. Sutherland

  10. SC-01. FOXM1B is expressed by neural and glioblastoma stem-like cells and regulates their proliferation Neuro Oncol (2012) 14(1), Suppl 3, iii145-iii153. K. Joshi, S. Gupta, S. Mazumder, Y. Okemoto, B. Angenieux, H. Kornblum,  I. Nakano.

  11. Nanoparticle Induced Cell Magneto-Rotation: Monitoring Morphology, Stress and Drug Sensitivity of a Suspended Single Cancer Cell PLoS ONE 2011, 6(12), e28475. R. Elbez, B.H. McNaughton, L. Patel, K.J. Pienta, R.Kopelman.

  12. Visualizing and Quantifying Acute Inflammation Using ICAM-1 Specific Nanoparticles and MRI Quantitative Susceptibility Mapping Annals BioMed Engineering 2012, 40(6), 1328-38, R. Wong, X. Chen, Y. Wang, X. Hu,  M. M. Jin

Fluorescent Quantum Dots

  1. Biomimetic fabrication of genetically engineered collagen peptide-assembled freestanding films reinforced by quantum dot joints Soft Matter, 2012, 8, 6871-5, Z. Wei, Y. Maeda, H. Matsui

  2. Calcium and EDTA Induced Folding and Unfolding of Calmodulin on Functionalized Quantum Dot Surfaces J. Nanoneuro 2012 2(1), 75-81, S.J. Kim, J. Blumling III, M.C. Davidson, H. Saad, S. Eun, G.A. Silva

  3. Geometrical confinement of quantum dots in porous nanobeads with ultraefficient fluorescence for cell-specific targeting and bioimaging J. Mater. Chem., 2012,22, 9568-9575, P. Chen ,  S. Hu ,  W. Hung ,  S.Chen, D. Liu

  4. Heme oxygenase expression as a biomarker of exposure to amphiphilic polymer-coated CdSe/ZnS quantum dots Nanotoxicology (Advanced online publication) L. A. McConnachie, C.C. White, D. Botta, M.E. Zadworny, D.P. Cox, R. P. Beyer, X. Hu, D. L. Eaton, X. Gao, T. J. Kavanagh

  5. Quantum dots trigger immunomodulation of the NFkB pathway in human skin cells Molecular Immunology 48 (2011) 1349– 1359. A.A. Romoser, P.L. Chen, J. M. Berg, C. Seabury, I.Ivanova, M.F. Criscitiello, C.M. Sayes

  6. Blood stage merozoite surface protein conjugated to nanoparticles induce potent parasite inhibitory antibodies Vaccine 2011, 29(48), 8898-908. K. Pusic, H. Xu, A. Stridiron, Z. Aguilar, A. Wang, G. Hui.

  7. Transport Behavior of Selected Nanoparticles with different Surface Coatings in Granular Porous Media coated with Pseudomonas aeruginosa Biofilm Environ Sci Technol (Advanced Online Publication) S. Tripathi, D. Champagne,  N. Tufenkji.

  8. Rapid, Sensitive, and Simultaneous Detection of Three Foodborne Pathogens Using Magnetic Nanobead-Based Immunoseparation and Quantum Dot-Based Multiplex Immunoassay J of Food Protection 2011, 74(12), 2039-2047. H. Wang, Y. Li, A. Wang, M. Slavik.

  9. Nanoporous poly(methyl methacrylate)-quantum dots nanocomposite fibers toward biomedical applications Polymer 2011, 52(25), 5817-5829. S. Wei, J. Sampathi, Z. Guo, N. Anumandla, D. Rutman, A. Kucknoor, L. James, A. Wang.

  10. Remote multi-color excitation using femtosecond propagating surface plasmon polaritons in gold films Optics Express, 2011, 19 (14), 13454. Y. Wang, X. Liu, D. Whitmore, W. Xing, E.O. Potma. 

  11. Site–Specific Sonoporation of Human Melanoma Cells at the Cellular Level Using High Lateral–Resolution Ultrasonic Micro–Transducer Arrays Biosensors and Bioelectronics, 2011, 27, 25– 33. M.Thein, A. Cheng, P.Khanna, C. Zhang, E. Park, D. Ahmed, C.J. Goodrich, F.Asphahani, F.Wu, N.B. Smith, C. Dong, X. Jiang, M. Zhang, J. Xu

  12. Efficient assembly of multi-walled carbon nanotube-CdSe/ZnS quantum dot hybrids with high biocompatibility and fluorescence property Colloids and Surfaces B: Biointerfaces, 2011, 87, 346– 352. Y. Zhang, W. Qin, H. Tanga, F. Yan, L. Tan, Q. Xie, M. Ma, Y. Zhang, S.Yao

Gold and Silver Nanoparticles

  1. Genotoxicity of Silver Nanoparticles in Vicia faba: A Pilot Study on the Environmental Monitoring of Nanoparticles Int. J. Environ. Res. Public Health 2012, 9, 1649-1662, A.K. Patlolla, A. Berry, L. May, P.B. Tchounwou

  2. Plasmonic Vesicles of Amphiphilic Gold Nanocrystals: Self-Assembly and External-Stimuli-Triggered Destruction JACS, 2011, 133 (28),  10760-3. J. Song, L. Cheng, A. Liu, J. Yin, M. Kuang, H. Duan